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Dosing Protocol The parallel escalation used in the REDEFINE trials, converted to U-100 units at 10 mg/mL total (5 mg/mL of each component)

In a mouse model of psychosocial stress, it was found that green tea had an anti-stress effect, which was due to the synergistic effect of L-theanine, epigallocatechin, and arginine, thus eliminating the antagonistic effect of caffeine and epigallocatechin gallate on psychological stress-induced adrenal hypertrophy (53)

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We observed that the wt strain showed a typical high bacterial load in lungs compared to other organs caused by the intranasal inoculation, as described [19] (Fig